Dr. Flaisher-Grinberg’s interests include the neuropharmacology of mood and anxiety disorders, the neurobiology of neurodegenerative and neurodevelopmental disorders (with an emphasis on autism spectrum disorders), and the development of novel animal models for different psychopathological conditions (such as obsessive compulsive disorder and bipolar disorder). Investigation and research are focused on the reciprocal relationship between environmental/behavioral processes and genetic/molecular factors. Methodological approach combines animal behavioral models, pharmacological interventions and molecular procedures, all designated to further our understanding of complex behaviors and mental illness.
Flaisher-Grinberg S., Einat H. Amphetamine-induced conditioned place preference test and modeling domains of bipolar disorder (Neuropsychopharmacology, 2011, 4, 18-24).
Flaisher-GrinbergS., Persaud SD., Loh HH, Wei LN. Stress-induced epigenetic regulation of κ-opioid receptor gene involves transcription factor c-Myc (PNAS, 2012, 109(23):9167-72).
Flaisher-Grinberg S., Tsai HC,. Feng X., Wei LN. Emotional regulatory function of Receptor Interacting protein 140 revealed in the ventromedial nucleus of the hypothalamus (Brain, Behavior and Immunity, 2014, 40:226-234).
Einat H., Flaisher-Grinberg S., Kara NZ. Partial effects of the AMPAkine CX717 in a strain specific battery of tests for manic-like behavior in black Swiss mice (Pharmacological Reports, 2015, 67(5):928-933).
Kara NZ,Flaisher-Grinberg S, Anderson GW, Agam G, Einat H. Antimanic-like effects of rapamycin in black Swiss mice: possible relevance to autophagy (accepted to Behavioural Pharmacology, 2017).
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