Saint Francis University

Dr. Charles Dameron
Associate Professor of Chemistry
Office: Sullivan 316
Phone: (814)-472-3871
Email: cdameron@francis.edu

Education
B.S., Texas A & M University
Ph.D., Texas A & M University
NIH Postdoctoral Fellow, University of Utah

Research Interests
Zinc and copper induced protein-protein interactions
Copper metabolism
Metalloregulation

Teaching
Chem 103 and 104
Human Chemistry I and II

Other courses:
(Courses taught at Duquesne University)
Chemistry 401 and 402 General Biochemistry I and II
Chemistry 325L and 425L Integrated Laboratory I and II
Chemistry 325R and 425R Integrated Laboratory I and II Recitation
Chemistry 475H Honors Senior Seminar 
Chemistry 490W Research
Chemistry 490H Honors Research
Chemistry 508 Biomolecular Structure and Function

Selected Publications

Pazehoski, K.O., Collins, T., Boyle,R.J., Jensen-Seaman, M.I., Dameron, C.T.(2007) Stalking Metal-linked Dimers.  J. Inorganic Biochem. In press.

Stokes, E.B, Stiff-Roberts, A.B, Dameron, C.T. (2006) Quantum Dots in Semi-conductor Optoelectronic Devices. Interface 15(4), 23-27. Our work was featured on the issue cover.

Cobine, P.A., McKay, R.T., Zangger, K., Dameron, C.T., Armitage, I.M. (2004) Solution structure of Cu6 metallothionein from the fungus Neurospora crassa. Eur. J. Biochem. 271 (21), 13-21.

Jones, C.E, Daly, N.L., Cobine, P.A, Craik, D.J. & Dameron, C. T. (2003) Structure and metal binding studies of the second copper binding domain of the Menkes ATPase. Journal of Structural Biology, 143(3), 209-18.

Cobine, P.A., McKay, R.T., Zangger, K., Dameron, C.T., Armitage, I.M. (2004) Solution structure of Cu6 metallothionein from the fungus Neurospora crassa. Eur. J. Biochem. 271 (21), 42-13-21.

Jones, C.E, Daly, N.L., Cobine, P.A, Craik, D.J. & Dameron, C. T. (2003) Structure and metal binding studies of the second copper binding domain of the Menkes ATPase. Journal of Structural Biology, 143(3), 209-18.

Lu, Z.H., Dameron, C.T. & Solioz, M.(2003) The Enterococcus hirae paradigm of copper homeostasis: Copper chaperone turnover, interactions, and transactions. BioMetals, 16, 137-143. 

Cobine, P.A., George, G.N., Jones, C.E., Wickramasinghe, W.A., Solioz, M. & Dameron, C.T. (2002) Copper Transfer from the Cu(I) Chaperone, CopZ, to the Repressor, Zn(II)CopY: Metal Coordination Environments and Protein Interactions. Biochemistry 41, 5822-5829.

Cobine, P.A., Jones, C.E. & Dameron, C.T. (2002) Role for zinc(II) in the copper(I) regulated protein CopY. Journal of Inorganic Biochemistry 88, 192-196.

Cobine, P., George, G.N., Winzor, D.J., Harrison, M.D., Mogahaddas, S. & Dameron, C.T. (2000) Stoichiometry of the Complex Formation between Copper(I) and the N-terminal Domain of the Menkes Protein. Biochemistry 39, 6857-6863.

Recent Presentations

“Natural metal induced dimerization and its role in regulation” invited lecture.  1^st Georgian Bay International Conference on Bioinorganic ChemistryCanBIC, Georgian Bay Canada, May 22-27 2007.

“Getting Hooked Up: A New Metal Binding Regulatory Motif” invited lecture in the Department of Chemistry at the University of Western Ontario, London Ontario Canada, May 25, 2006. 

“From Cells to Coordination Chemistry and Back Again” invited lecture in the Department of Chemistry and Biochemistry Duquesne University, September 2005.

“Metal Links to Regulation” invited lecture at the summer SGI Summit on High Performance Computing for the Advancement of Science,  Duquesne University, May 27, 2005. 

“Place-holding Roles for Zinc in the Formation of Mature 6Cu(I) N. crassa Metallothionein and 2Cu(I) E. hirae CopY invited lecture.  4^th International Meeting on “Copper Homeostasis and its Disorders: Molecular and Cellular Aspects”, Ischia Italy, October 23-28, 2004.

“Pre-stabilization of a Copper(I) Binding Site with Zinc” invited lecture.  19^th Annual American Chemical Society Pittsburgh Section Student Affiliates Meeting, Duquesne University, April 2004.

“A critical role for Zinc in the Action of a Copper Regulated Repressor” Midwest Metals Meeting-Metals in Biology 2, held at the Washington University in St. Louis, Chicago, May 16-18, 2003.

Patents

United States Patent Application Serial No. 11/751,850, Filed 05/22/07
      Title:  Self-Assembled Proteins and Related Methods and Protein Structures

Affiliations

Alpha Chi Sigma Fraternity

Community Service

Grants
Ad hoc reviewer for: NIH, NSF, Grants.

Journal
Ad hoc reviewer for:

Journal of Inorganic Biochemistry
Biochemica et Biophysica Acta
Trends in Biological Sciences.